Differin Gel Adapalene Gel 0.1% Acne Treatment (0.5 oz + 1.6 oz.) 


$ 43.99 


Differin Gel is the first and only FDA-approved full prescription strength retinoid acne treatment now available without a prescription. Until now, 99% of all OTC acne medications in the US used only two different types of active ingredients. Differin Gel contains adapalene, a multi-benefit dermatologist-recommended retinoid that clears and prevents acne, which helps restore your skin’s natural tone and texture. It's the newest active ingredient in over-the-counter acne treatment in over 30 years. Now you can clear your acne with the power of Rx.

1. CLEANSE: Wash your face with a gentle, non-drying cleanser like Differin Balancing Cleanser
2. TREAT: Simply spread a thin layer of Differin Gel to the affected area once a day. This is NOT a spot treatment
3. MOISTURIZE: To help maintain healthy skin, use a moisturizer like Differin Balancing Moisturizer after each application. Use of a moisturizer may help decrease dryness and other signs of irritation




  • First new, FDA-approved active ingredient to the OTC acne category in over 30 years
  • In clinical studies, Differin Gel provided nearly a 60% average reduction in lesions after 12 weeks
  • Will continue to improve with further use
  • One 0.5 oz. gel
  • One 1.6 oz. gel
  • For the treatment of acne
  • Once daily topical retinoid